Estriol vaginal cream
Estriol is not made commercially in the United States, so compounding is how a prescription for it gets filled. We prepare it to order at the strength on your prescription.
WOMEN’S HEALTH · VAGINAL ESTROGEN
Vaginal estrogen,
made for you.
Vaginal dryness, irritation and discomfort are some of the most common changes around menopause. When your prescriber orders a vaginal estrogen, we prepare it for you in a base that suits you and ship it to your door, in all 50 states and the District of Columbia.
PCAB accredited · licensed in all 50 states + DC
Estriol and estradiol creamsHypoallergenic bases availableShipped to all 50 states + DC423-975-0597
WHAT IS HAPPENING
A common change
around menopause.
These changes are very common, and they are a routine topic for clinicians who care for women in midlife. If they are affecting you, they are worth raising with your prescriber. Our guide on how to ask your doctor about compounded medication can help you start that conversation.
The tissues of the vagina, vulva, urethra and bladder are rich in estrogen receptors. As estrogen falls in the years around menopause, those tissues can become thinner, drier and less elastic. Clinicians call the resulting changes the genitourinary syndrome of menopause, and they include dryness, irritation, discomfort during sex and needing to urinate more often.
Vaginal estrogen is applied directly to the vaginal tissue, most often as a cream, which is why it is described as local therapy. That makes it different from systemic hormone therapy, which is meant to reach the whole body.
Two estrogens are commonly prescribed for vaginal use: estradiol, the main estrogen the ovaries make before menopause, and estriol, a weaker estrogen that is not available as a commercially manufactured product in the United States. A prescriber may choose a compounded preparation to use estriol, to combine it with DHEA, or to use a base without ingredients a patient reacts to. Which estrogen, which base and how often are decisions for you and your prescriber.
HOW WE CAN HELP
What we prepare for you.
Estradiol vaginal cream
Estradiol prepared as a vaginal cream in the base your prescriber chooses, including a hypoallergenic base.
Estriol with DHEA
Estriol and DHEA combined in one vaginal cream, for prescribers who want both in a single preparation.
Hyaluronic acid vaginal base
A hyaluronic acid vaginal base, which your prescriber can order on its own or as the base for a preparation.
Made for sensitive skin
Hypoallergenic, dye-free and filler-free options for women who react to ingredients in other products. A pharmacist reviews every formulation before it is made.
Wherever you live
We are PCAB accredited and licensed in all 50 states and the District of Columbia, and we ship your preparation to your home.
More for you: Women’s health compounding · Estradiol patch alternatives · Hormone replacement therapy · Vaginal dryness in menopause: the longer read
GETTING IT FILLED
Three steps,
and we handle the rest.
Your prescriber can send a new prescription to us, or we can transfer one you already have. Prescriber details are on our prescriber page.
- 01
Your prescriber sends us the prescription
Our details for prescribers are on our prescriber page. If you already have a prescription at another pharmacy, we can transfer it for you.
- 02
We confirm the details with you
A member of our team confirms the price with you before anything is processed, made, or shipped.
- 03
We compound it and ship it to you
We have a 48-hour compounding time on most preparations. Shipping time is additional.
QUESTIONS WOMEN ASK US
The things
worth knowing.
Call 423-975-0597 for current pricing and shipping options for your state.
How is vaginal estrogen different from hormone therapy?
Vaginal estrogen is applied directly to the vaginal tissue and is described as local therapy. Systemic hormone therapy, such as an estradiol cream applied to the skin, is meant to reach the whole body. Some women use vaginal estrogen on its own and some use both, as their prescriber decides.
What is estriol, and why is it compounded?
Estriol is a weaker estrogen that the body makes in larger amounts during pregnancy. It is not available as a commercially manufactured product in the United States, so a prescription for estriol is prepared by a compounding pharmacy.
Which vaginal preparations do you compound?
Estradiol vaginal cream, estriol vaginal cream, estriol combined with DHEA in one vaginal cream, and a hyaluronic acid vaginal base. Each is made to order at the strength your prescriber writes, and hypoallergenic, dye-free and filler-free options are available.
Do I need a prescription?
Yes. Vaginal estrogen is a prescription medication, so your prescriber decides whether it is right for you, which estrogen to use and how often to use it. We do not prescribe; we prepare what your prescriber orders.
Can you ship to my state, and how long does it take?
We are licensed in all 50 states and the District of Columbia. We have a 48-hour compounding time on most preparations. Shipping time is additional and varies by destination. A member of our team confirms the price with you before anything is processed, made, or shipped.
Compounded preparations are not reviewed or approved by the FDA for safety or efficacy. This page is for education and reflects what we see in clinical practice; it is not medical advice. Decisions about your care rest with your prescriber, who also orders and interprets any lab work.